Liposomal NMN and Resveratrol

In liposomal supplement manufacturing, ultra-pure water is essential to ensure product stability, safety, and effectiveness. One of the key steps in achieving this high level of water purity is the use of deionised water (DI water).

Deionised water is created by removing the mineral ions (such as calcium, magnesium, sodium, chloride, sulfate and carbonate) that are commonly found in tap or distilled water. This is typically done using ion exchange resins, which attract and trap positively and negatively charged particles (ions). The process involves passing water through a mixed-bed resin or through sequential cation and anion exchange columns, which exchange undesirable ions for hydrogen (H⁺) and hydroxide (OH⁻) ions. These combine to form pure water (H₂O) as the by-product.

While deionisation removes charged particles, it does not eliminate organic contaminants, bacteria, or particulates.

For this reason, SAIFx® Technology used in lipolife® formulations takes it a step further to achieve ultra-pure water by integrating additional purification steps. The resulting ultra-pure water is chemically neutral and microbiologically clean, which is crucial for liposomal formulations. Any impurities, especially ions or microbes, could compromise the integrity of the phospholipid bilayers that form liposomes, affect shelf stability, or introduce contamination into the final product.

Phospholipids are the primary building blocks of liposomes, forming the bilayer membrane that encapsulates and protects the active ingredients. If the phospholipids are poor quality or degraded, the liposome may break apart, leading to leakage or degradation of the supplement’s active compounds.

lipolife® use non-allergenic, non-GMO, sunflower phospholipids from world-leading producer, Lipoid®.

Lipoid® is an industry pioneer and has been setting the standard in lipid production for over 45 years.

By using Lipoid® as the foundation of our liposomal formulations, lipolife® ensure our liposomes survive through the digestive system and effectively fuse with cell membranes, maximising nutrient uptake.

Trans-resveratrol is the biologically active form of resveratrol, a polyphenol renowned for its antioxidant, anti-inflammatory and anti-ageing properties. Sourced from Japanese knotweed (Polygonum cuspidatum), one of the richest and most sustainable natural sources, trans-resveratrol is the preferred form for high-quality supplements due to its high purity and potency.

This plant-based compound mimics the effects of calorie restriction at the cellular level, activating sirtuins and promoting healthy mitochondrial function, which are key mechanisms in longevity and cellular repair.

Research has shown that trans-resveratrol supports cardiovascular health, helps regulate oxidative stress and may enhance cognitive performance and metabolic balance. Japanese knotweed-derived trans-resveratrol is particularly valued for its consistent quality, high concentration of the active isomer and excellent bioactivity when formulated properly.

NMN (β-Nicotinamide Mononucleotide) is a bioactive nucleotide derived from niacin (vitamin B3). It is a direct precursor to NAD⁺ (nicotinamide adenine dinucleotide).