AquaLOX is a water-soluble version of one of the world’s best-selling joint health ingredients, 5-LOXIN.
5-LOXIN® has been clinically demonstrated to improve joint comfort and protect against cartilage degradation.
A novel Boswellia serrata extract enriched with 30% 3-O-acetyl-11-keto-beta-boswellic acid (AKBA), AquaLOX exhibits potential anti-inflammatory properties by inhibiting the 5-lipoxygenase enzyme.
It has been the subject of 13 pre-clinical studies and 2 human clinical trials.
One of the key features of 5-LOXIN in any formulation is the clinical work that has demonstrated efficacy starting at 7 days – at a significantly lower dose (100 mg) than other joint health ingredients. This fast efficacy and low dose allow 5-LOXIN to compete with non-natural or over-the-counter solutions.
Beyond joint comfort and flexibility improvements, 5-LOXIN also positively impacts biological markers associated with joint health and inflammation, including TNFa, CRP, and IL-6. It was also shown to significantly inhibit matrix metalloproteinase (MMP-3), an enzyme that breaks down cartilage, collagen and connective tissues.